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The Effect of C-Terminal Helix on the Stability of FF Domain Studied by Molecular Dynamics Simulation

To investigate the effect of C-terminal helix on the stability of the FF domain, we studied the native domain FF3-71 from human HYPA/FBP11 and the truncated version FF3-60 with C-terminal helix being deleted by molecular dynamics simulations with GROMACS package and GROMOS 43A1 force field. The resu...

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Detalles Bibliográficos
Autores principales: Zhao, Liling, Cao, Zanxia, Wang, Jihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291988/
https://www.ncbi.nlm.nih.gov/pubmed/22408419
http://dx.doi.org/10.3390/ijms13021720