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Zuonin B Inhibits Lipopolysaccharide-Induced Inflammation via Downregulation of the ERK1/2 and JNK Pathways in RAW264.7 Macrophages
We investigated whether Zuonin B exerts immunological effects on RAW264.7 cells. Zuonin B, isolated from flower buds of Daphne genkwa, suppressed the levels of nitric oxide and prostaglandin E(2), as well as proinflammatory cytokines, such as tumor necrosis factor-α and interleukin-(IL-) 6, in lipop...
Autores principales: | Lee, Mee-Young, Yuk, Ji-Eun, Kwon, Ok-Kyung, Oh, Sei-Ryang, Lee, Hyeong-Kyu, Ahn, Kyung-Seop |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292044/ https://www.ncbi.nlm.nih.gov/pubmed/22454678 http://dx.doi.org/10.1155/2012/728196 |
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