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Zuonin B Inhibits Lipopolysaccharide-Induced Inflammation via Downregulation of the ERK1/2 and JNK Pathways in RAW264.7 Macrophages

We investigated whether Zuonin B exerts immunological effects on RAW264.7 cells. Zuonin B, isolated from flower buds of Daphne genkwa, suppressed the levels of nitric oxide and prostaglandin E(2), as well as proinflammatory cytokines, such as tumor necrosis factor-α and interleukin-(IL-) 6, in lipop...

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Detalles Bibliográficos
Autores principales: Lee, Mee-Young, Yuk, Ji-Eun, Kwon, Ok-Kyung, Oh, Sei-Ryang, Lee, Hyeong-Kyu, Ahn, Kyung-Seop
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292044/
https://www.ncbi.nlm.nih.gov/pubmed/22454678
http://dx.doi.org/10.1155/2012/728196

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