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Ablation of PI3K p110-α Prevents High-Fat Diet–Induced Liver Steatosis

OBJECTIVE: To determine whether the phosphoinositide 3-kinase (PI3K) catalytic subunits p110-α and p110-β play a role in liver steatosis induced by a high-fat diet (HFD). RESEARCH DESIGN AND METHODS: Liver-specific p110-α and p110-β knockout mice and control animals for each group were fed an HFD or...

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Detalles Bibliográficos
Autores principales:	Chattopadhyay, Mohar, Selinger, Elzbieta S., Ballou, Lisa M., Lin, Richard Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292322/ https://www.ncbi.nlm.nih.gov/pubmed/21464441 http://dx.doi.org/10.2337/db10-0869

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