Biophysical and structural considerations for protein sequence evolution

BACKGROUND: Protein sequence evolution is constrained by the biophysics of folding and function, causing interdependence between interacting sites in the sequence. However, current site-independent models of sequence evolutions do not take this into account. Recent attempts to integrate the influenc...

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Detalles Bibliográficos
Autores principales: Grahnen, Johan A, Nandakumar, Priyanka, Kubelka, Jan, Liberles, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292521/
https://www.ncbi.nlm.nih.gov/pubmed/22171550
http://dx.doi.org/10.1186/1471-2148-11-361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292521/
https://www.ncbi.nlm.nih.gov/pubmed/22171550
http://dx.doi.org/10.1186/1471-2148-11-361

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