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Biophysical and structural considerations for protein sequence evolution
BACKGROUND: Protein sequence evolution is constrained by the biophysics of folding and function, causing interdependence between interacting sites in the sequence. However, current site-independent models of sequence evolutions do not take this into account. Recent attempts to integrate the influenc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292521/ https://www.ncbi.nlm.nih.gov/pubmed/22171550 http://dx.doi.org/10.1186/1471-2148-11-361 |