Glucocorticoid-Induced Leucine Zipper (GILZ) Antagonizes TNF-α Inhibition of Mesenchymal Stem Cell Osteogenic Differentiation

Tumor necrosis factor-alpha (TNF-α) is a potent proinflammatory cytokine that inhibits osteoblast differentiation while stimulating osteoclast differentiation and bone resorption. TNF-α activates MAP kinase pathway leading to inhibition of osterix (Osx) expression. TNF-α also induces the expression...

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Detalles Bibliográficos
Autores principales: He, Linlin, Yang, Nianlan, Isales, Carlos M., Shi, Xing-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292550/
https://www.ncbi.nlm.nih.gov/pubmed/22396737
http://dx.doi.org/10.1371/journal.pone.0031717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292550/
https://www.ncbi.nlm.nih.gov/pubmed/22396737
http://dx.doi.org/10.1371/journal.pone.0031717

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