A Comprehensive Investigation on Common Polymorphisms in the MDR1/ABCB1 Transporter Gene and Susceptibility to Colorectal Cancer

ATP Binding Cassette B1 (ABCB1) is a transporter with a broad substrate specificity involved in the elimination of several carcinogens from the gut. Several polymorphic variants within the ABCB1 gene have been reported as modulators of ABCB1-mediated transport. We investigated the impact of ABCB1 ge...

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Detalles Bibliográficos
Autores principales: Campa, Daniele, Sainz, Juan, Pardini, Barbara, Vodickova, Ludmila, Naccarati, Alessio, Rudolph, Anja, Novotny, Jan, Försti, Asta, Buch, Stephan, von Schönfels, Witigo, Schafmayer, Clemens, Völzke, Henry, Hoffmeister, Michael, Frank, Bernd, Barale, Roberto, Hemminki, Kari, Hampe, Jochen, Chang-Claude, Jenny, Brenner, Hermann, Vodicka, Pavel, Canzian, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292569/
https://www.ncbi.nlm.nih.gov/pubmed/22396794
http://dx.doi.org/10.1371/journal.pone.0032784

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