The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

BACKGROUND: The conserved CD4 binding site (CD4bs) on HIV-1 gp120 is a major target for vaccines. It is a priority to determine sites and structures within the CD4bs that are important for inclusion in vaccines. We studied a gp120 pocket penetrated by W100 of the potent CD4bs monoclonal antibody (ma...

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Detalles Bibliográficos
Autores principales: Dueñas-Decamp, Maria J, O'Connell, Olivia J, Corti, Davide, Zolla-Pazner, Susan, Clapham, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292835/
https://www.ncbi.nlm.nih.gov/pubmed/22284192
http://dx.doi.org/10.1186/1742-4690-9-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292835/
https://www.ncbi.nlm.nih.gov/pubmed/22284192
http://dx.doi.org/10.1186/1742-4690-9-9

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