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Integrative Analysis of Response to Tamoxifen Treatment in ER-Positive Breast Cancer Using GWAS Information and Transcription Profiling

Variable response and resistance to tamoxifen treatment in breast cancer patients remains a major clinical problem. To determine whether genes and biological pathways containing SNPs associated with risk for breast cancer are dysregulated in response to tamoxifen treatment, we performed analysis com...

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Detalles Bibliográficos
Autores principales: Hicks, Chindo, Kumar, Ranjit, Pannuti, Antonio, Miele, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292850/
https://www.ncbi.nlm.nih.gov/pubmed/22399860
http://dx.doi.org/10.4137/BCBCR.S8652