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Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

Carbonic anhydrase IX (CAIX) is a hypoxia-inducible enzyme that is overexpressed by cancer cells from many tumor types, and is a component of the pH regulatory system invoked by these cells to combat the deleterious effects of a high rate of glycolytic metabolism. CAIX functions to help produce and...

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Detalles Bibliográficos
Autores principales:	McDonald, Paul C., Winum, Jean-Yves, Supuran, Claudiu T., Dedhar, Shoukat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Research Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292895/ https://www.ncbi.nlm.nih.gov/pubmed/22289741

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