Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

Cellular senescence arrests the proliferation of mammalian cells at risk for neoplastic transformation, and is also associated with aging. However, the factors that cause cellular senescence during aging are unclear. Excessive reactive oxygen species (ROS) have been shown to cause cellular senescenc...

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Detalles Bibliográficos
Autores principales: Velarde, Michael C., Flynn, James M., Day, Nicholas U., Melov, Simon, Campisi, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292901/
https://www.ncbi.nlm.nih.gov/pubmed/22278880

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