Age-related resistance of skeletal muscle-derived progenitor cells to SPARC may explain a shift from myogenesis to adipogenesis

Aging causes phenotypic changes in skeletal muscle progenitor cells (SMPCs) that lead to the loss of myogenicity and adipogenesis. Secreted protein acidic and rich in cysteine (SPARC), which is secreted from SMPCs, stimulates myogenesis and inhibits adipogenesis. The present study aimed to examine w...

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Detalles Bibliográficos
Autores principales: Nakamura, Serena Katsuyuki, Nakano, Shin-ichi, Miyoshi, Takahiro, Yamanouchi, Keitaro, Matsuwaki, Takashi, Nishihara, Masugi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292904/
https://www.ncbi.nlm.nih.gov/pubmed/22289652

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