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A naturally occurring carotenoid, lutein, reduces PDGF and H(2)O(2 )signaling and compromised migration in cultured vascular smooth muscle cells

BACKGROUND: Platelet-derived growth factor (PDGF) is a potent stimulator of growth and motility of vascular smooth muscle cells (VSMCs). Abnormalities of PDGF/PDGF receptor (PDGFR) are thought to contribute to vascular diseases and malignancy. We previously showed that a carotenoid, lycopene, can di...

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Detalles Bibliográficos
Autores principales:	Lo, Huey-Ming, Tsai, Yih-Jeng, Du, Wen-Yuan, Tsou, Chih-Jen, Wu, Wen-Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292940/ https://www.ncbi.nlm.nih.gov/pubmed/22313606 http://dx.doi.org/10.1186/1423-0127-19-18

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