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Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells

BACKGROUND: Aneuploidy has been acknowledged as a major source of genomic instability in cancer, and it is often considered the result of chromosome segregation errors including those caused by defects in genes controlling the mitotic spindle assembly, centrosome duplication and cell-cycle checkpoin...

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Detalles Bibliográficos
Autores principales:	Barra, Viviana, Schillaci, Tiziana, Lentini, Laura, Costa, Giuseppe, Di Leonardo, Aldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292948/ https://www.ncbi.nlm.nih.gov/pubmed/22305267 http://dx.doi.org/10.1186/1747-1028-7-2

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