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Why do results conflict regarding the prognostic value of the methylation status in colon cancers? the role of the preservation method
BACKGROUND: In colorectal carcinoma, extensive gene promoter hypermethylation is called the CpG island methylator phenotype (CIMP). Explaining why studies on CIMP and survival yield conflicting results is essential. Most experiments to measure DNA methylation rely on the sodium bisulfite conversion...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293017/ https://www.ncbi.nlm.nih.gov/pubmed/22243995 http://dx.doi.org/10.1186/1471-2407-12-12 |