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Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects

BACKGROUND: High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the pharmacokinetic profile of oral thiamine hydrochloride at 100 mg, 500 mg and 1500 mg doses in healthy subjects. METHODS: This was a rando...

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Detalles Bibliográficos
Autores principales: Smithline, Howard A, Donnino, Michael, Greenblatt, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293077/
https://www.ncbi.nlm.nih.gov/pubmed/22305197
http://dx.doi.org/10.1186/1472-6904-12-4