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LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and G(i)α dependent PI-3kinase signalling

COPD is a disease of innate immunity and bacterial infections are a dominant cause of exacerbations in the later stages resulting in poor health and high mortality. The pathogen-associated molecular pattern (PAMP) lipopolysaccharide (LPS) is sensed by immune cells through activation of the toll-like...

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Detalles Bibliográficos
Autores principales:	Ngkelo, Anta, Meja, Koremu, Yeadon, Mike, Adcock, Ian, Kirkham, Paul A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293082/ https://www.ncbi.nlm.nih.gov/pubmed/22239975 http://dx.doi.org/10.1186/1476-9255-9-1

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