Cargando…
TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection
BACKGROUND: We have previously shown that toll-like receptor 3 (TLR3)-mediated signaling plays an important role in the induction of innate cytokine responses to Theiler's murine encephalomyelitis virus (TMEV) infection. In addition, cytokine levels produced after TMEV infection are significant...
Autores principales: | Jin, Young-Hee, Kaneyama, Tomoki, Kang, Min Hyung, Kang, Hyun Seok, Koh, Chang-Sung, Kim, Byung S |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293102/ https://www.ncbi.nlm.nih.gov/pubmed/22189096 http://dx.doi.org/10.1186/1742-2094-8-178 |
Ejemplares similares
-
Transgenic expression of non-structural genes of Theiler’s virus suppresses initial viral replication and pathogenesis of demyelination
por: Kang, Hyun Seok, et al.
Publicado: (2016) -
Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus
por: Kim, Byung S.
Publicado: (2023) -
Immune mechanisms of Theiler's virus-induced demyelination
por: Kim, Byung Suk, et al.
Publicado: (1999) -
Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler’s Virus-Induced Demyelinating Disease
por: Kim, Byung S.
Publicado: (2021) -
Viral models of multiple sclerosis: Neurodegeneration and demyelination in mice infected with Theiler's virus
por: Mecha, Miriam, et al.
Publicado: (2013)