Unique domain appended to vertebrate tRNA synthetase is essential for vascular development

New domains were progressively added to cytoplasmic aminoacyl transfer RNA (tRNA) synthetases during evolution. One example is the UNE-S domain, appended to seryl-tRNA synthetase (SerRS) in species that developed closed circulatory systems. Here we show using solution and crystal structure analyses...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoling, Shi, Yi, Zhang, Hui-Min, Swindell, Eric C., Marshall, Alan G., Guo, Min, Kishi, Shuji, Yang, Xiang-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293412/
https://www.ncbi.nlm.nih.gov/pubmed/22353712
http://dx.doi.org/10.1038/ncomms1686

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