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PPARγ contributes to PKM2 and HK2 expression in fatty liver

Rapidly proliferating cells promote glycolysis in aerobic conditions, to increase growth rate. Expression of specific glycolytic enzymes, namely pyruvate kinase M2 and hexokinase 2, concurs to this metabolic adaptation, as their kinetics and intracellular localization favour biosynthetic processes r...

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Detalles Bibliográficos
Autores principales:	Panasyuk, Ganna, Espeillac, Catherine, Chauvin, Céline, Pradelli, Ludivine A., Horie, Yasuo, Suzuki, Akira, Annicotte, Jean-Sebastien, Fajas, Lluis, Foretz, Marc, Verdeguer, Francisco, Pontoglio, Marco, Ferré, Pascal, Scoazec, Jean-Yves, Birnbaum, Morris J., Ricci, Jean-Ehrland, Pende, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293420/ https://www.ncbi.nlm.nih.gov/pubmed/22334075 http://dx.doi.org/10.1038/ncomms1667

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