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Structural Analysis of the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Intracellular Domain Reveals a Conserved Interaction Epitope

Plasmodium falciparum-infected red blood cells adhere to endothelial cells, thereby obstructing the microvasculature. Erythrocyte adherence is directly associated with severe malaria and increased disease lethality, and it is mediated by the PfEMP1 family. PfEMP1 clustering in knob-like protrusions...

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Detalles Bibliográficos
Autores principales:	Mayer, Christina, Slater, Leanne, Erat, Michele C., Konrat, Robert, Vakonakis, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293552/ https://www.ncbi.nlm.nih.gov/pubmed/22249178 http://dx.doi.org/10.1074/jbc.M111.330779

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