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Bone Marrow p16(INK4a)-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development
OBJECTIVE: A genomic region near the CDKN2A locus, encoding p16(INK4a), has been associated to type 2 diabetes and atherosclerotic vascular disease, conditions in which inflammation plays an important role. Recently, we found that deficiency of p16(INK4a) results in decreased inflammatory signaling...
Autores principales: | Wouters, Kristiaan, Cudejko, Céline, Gijbels, Marion J. J., Fuentes, Lucia, Bantubungi, Kadiombo, Vanhoutte, Jonathan, Dièvart, Rebecca, Paquet, Charlotte, Bouchaert, Emmanuel, Hannou, Sarah Anissa, Gizard, Florence, Tailleux, Anne, de Winther, Menno P. J., Staels, Bart, Paumelle, Réjane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293804/ https://www.ncbi.nlm.nih.gov/pubmed/22403661 http://dx.doi.org/10.1371/journal.pone.0032440 |
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