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Lost in folding space? Comparing four variants of the thermodynamic model for RNA secondary structure prediction

BACKGROUND: Many bioinformatics tools for RNA secondary structure analysis are based on a thermodynamic model of RNA folding. They predict a single, "optimal" structure by free energy minimization, they enumerate near-optimal structures, they compute base pair probabilities and dot plots,...

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Detalles Bibliográficos
Autores principales: Janssen, Stefan, Schudoma, Christian, Steger, Gerhard, Giegerich, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293930/
https://www.ncbi.nlm.nih.gov/pubmed/22051375
http://dx.doi.org/10.1186/1471-2105-12-429