Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene

About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic...

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Detalles Bibliográficos
Autores principales: Min, Jun Won, Park, Youn Joon, Kim, Hee Jin, Chang, Myung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294113/
https://www.ncbi.nlm.nih.gov/pubmed/22403753
http://dx.doi.org/10.4174/jkss.2012.82.3.185
Descripción
Sumario:About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic test detected a L790F germline mutation of RET oncogene. The author found a necessity for genetic tests in cases of young-age, bilateral pheochromocytoma.

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