Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene

About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Min, Jun Won, Park, Youn Joon, Kim, Hee Jin, Chang, Myung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294113/
https://www.ncbi.nlm.nih.gov/pubmed/22403753
http://dx.doi.org/10.4174/jkss.2012.82.3.185
_version_ 1782225466159005696
author Min, Jun Won
Park, Youn Joon
Kim, Hee Jin
Chang, Myung-Chul
author_facet Min, Jun Won
Park, Youn Joon
Kim, Hee Jin
Chang, Myung-Chul
author_sort Min, Jun Won
collection PubMed
description About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic test detected a L790F germline mutation of RET oncogene. The author found a necessity for genetic tests in cases of young-age, bilateral pheochromocytoma.
format Online
Article
Text
id pubmed-3294113
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher The Korean Surgical Society
record_format MEDLINE/PubMed
spelling pubmed-32941132012-03-08 Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene Min, Jun Won Park, Youn Joon Kim, Hee Jin Chang, Myung-Chul J Korean Surg Soc Case Report About ten percent of pheochromocytomas are associated with familial syndrome. Hereditary pheochromocytoma has characteristics of early onset, multifocality and bilaterality. We experienced a case of 44-year-old man with bilateral pheochromocytoma without evidence of medullary thyroid cancer. Genetic test detected a L790F germline mutation of RET oncogene. The author found a necessity for genetic tests in cases of young-age, bilateral pheochromocytoma. The Korean Surgical Society 2012-03 2012-02-27 /pmc/articles/PMC3294113/ /pubmed/22403753 http://dx.doi.org/10.4174/jkss.2012.82.3.185 Text en Copyright © 2012, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Min, Jun Won
Park, Youn Joon
Kim, Hee Jin
Chang, Myung-Chul
Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title_full Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title_fullStr Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title_full_unstemmed Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title_short Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene
title_sort bilateral adrenal pheochromocytoma with a germline l790f mutation in the ret oncogene
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294113/
https://www.ncbi.nlm.nih.gov/pubmed/22403753
http://dx.doi.org/10.4174/jkss.2012.82.3.185
work_keys_str_mv AT minjunwon bilateraladrenalpheochromocytomawithagermlinel790fmutationintheretoncogene
AT parkyounjoon bilateraladrenalpheochromocytomawithagermlinel790fmutationintheretoncogene
AT kimheejin bilateraladrenalpheochromocytomawithagermlinel790fmutationintheretoncogene
AT changmyungchul bilateraladrenalpheochromocytomawithagermlinel790fmutationintheretoncogene

Ejemplares similares