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Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis

A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diag...

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Detalles Bibliográficos
Autores principales: Lembo, Tiziana, Niezgoda, Michael, Velasco-Villa, Andrés, Cleaveland, Sarah, Ernest, Eblate, Rupprecht, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294322/
https://www.ncbi.nlm.nih.gov/pubmed/16494761
http://dx.doi.org/10.3201/eid1202.050812
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author Lembo, Tiziana
Niezgoda, Michael
Velasco-Villa, Andrés
Cleaveland, Sarah
Ernest, Eblate
Rupprecht, Charles E.
author_facet Lembo, Tiziana
Niezgoda, Michael
Velasco-Villa, Andrés
Cleaveland, Sarah
Ernest, Eblate
Rupprecht, Charles E.
author_sort Lembo, Tiziana
collection PubMed
description A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific.
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spelling pubmed-32943222012-03-08 Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis Lembo, Tiziana Niezgoda, Michael Velasco-Villa, Andrés Cleaveland, Sarah Ernest, Eblate Rupprecht, Charles E. Emerg Infect Dis Dispatch A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific. Centers for Disease Control and Prevention 2006-02 /pmc/articles/PMC3294322/ /pubmed/16494761 http://dx.doi.org/10.3201/eid1202.050812 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Lembo, Tiziana
Niezgoda, Michael
Velasco-Villa, Andrés
Cleaveland, Sarah
Ernest, Eblate
Rupprecht, Charles E.
Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title_full Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title_fullStr Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title_full_unstemmed Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title_short Evaluation of a Direct, Rapid Immunohistochemical Test for Rabies Diagnosis
title_sort evaluation of a direct, rapid immunohistochemical test for rabies diagnosis
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294322/
https://www.ncbi.nlm.nih.gov/pubmed/16494761
http://dx.doi.org/10.3201/eid1202.050812
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