Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 alle...

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Detalles Bibliográficos
Autores principales: Keynan, Yoav, Juno, Jennifer, Meyers, Adrienne, Ball, T. Blake, Kumar, Anand, Rubinstein, Ethan, Fowke, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2010
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294998/
https://www.ncbi.nlm.nih.gov/pubmed/20875295
http://dx.doi.org/10.3201/eid1610.100108
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author Keynan, Yoav
Juno, Jennifer
Meyers, Adrienne
Ball, T. Blake
Kumar, Anand
Rubinstein, Ethan
Fowke, Keith R.
author_facet Keynan, Yoav
Juno, Jennifer
Meyers, Adrienne
Ball, T. Blake
Kumar, Anand
Rubinstein, Ethan
Fowke, Keith R.
author_sort Keynan, Yoav
collection PubMed
description Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.
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spelling pubmed-32949982012-03-08 Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009 Keynan, Yoav Juno, Jennifer Meyers, Adrienne Ball, T. Blake Kumar, Anand Rubinstein, Ethan Fowke, Keith R. Emerg Infect Dis Dispatch Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease. Centers for Disease Control and Prevention 2010-10 /pmc/articles/PMC3294998/ /pubmed/20875295 http://dx.doi.org/10.3201/eid1610.100108 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Keynan, Yoav
Juno, Jennifer
Meyers, Adrienne
Ball, T. Blake
Kumar, Anand
Rubinstein, Ethan
Fowke, Keith R.
Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title_full Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title_fullStr Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title_full_unstemmed Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title_short Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009
title_sort chemokine receptor 5 δ32 allele in patients with severe pandemic (h1n1) 2009
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294998/
https://www.ncbi.nlm.nih.gov/pubmed/20875295
http://dx.doi.org/10.3201/eid1610.100108
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