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RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome

AIMS: To establish the safety, tolerability and most promising regimen of darexaban (YM150), a novel, oral, direct factor Xa inhibitor, for prevention of ischaemic events in acute coronary syndrome (ACS). METHODS: In a 26-week, multi-centre, double-blind, randomized, parallel-group study, 1279 patie...

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Detalles Bibliográficos
Autores principales:	Steg, Ph. Gabriel, Mehta, Shamir R., Jukema, J. Wouter, Lip, Gregory Y.H., Gibson, C. Michael, Kovar, Frantisek, Kala, Petr, Garcia-Hernandez, Alberto, Renfurm, Ronny W., Granger, Christopher B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Fasttrack
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295208/ https://www.ncbi.nlm.nih.gov/pubmed/21878434 http://dx.doi.org/10.1093/eurheartj/ehr334

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