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Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy

A 36-year-old man visited our hospital because of blurred vision and redness of the conjunctiva. Slit-lamp examination showed panuveitis. Two days later, he suddenly experienced dizziness, speech disturbance, paralysis of his right extremities, and gait disturbances. Neurological examinations sugges...

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Autores principales: Yoshida-Hata, Natsuyo, Yashiro, Shigeko, Arai, Noritoshi, Takeuchi, Sousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295379/
https://www.ncbi.nlm.nih.gov/pubmed/22431930
http://dx.doi.org/10.1155/2012/356743
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author Yoshida-Hata, Natsuyo
Yashiro, Shigeko
Arai, Noritoshi
Takeuchi, Sousuke
author_facet Yoshida-Hata, Natsuyo
Yashiro, Shigeko
Arai, Noritoshi
Takeuchi, Sousuke
author_sort Yoshida-Hata, Natsuyo
collection PubMed
description A 36-year-old man visited our hospital because of blurred vision and redness of the conjunctiva. Slit-lamp examination showed panuveitis. Two days later, he suddenly experienced dizziness, speech disturbance, paralysis of his right extremities, and gait disturbances. Neurological examinations suggested that his symptoms were caused by a left lateral medullary lesion. He also had erythema mainly on his trunk. Magnetic resonance imaging (MRI) of his brain demonstrated a small infarct on the left side of the medulla oblongata. Clinical presentation and MRI findings were consistent with the diagnosis of a Wallenberg's syndrome. He also had bilateral hilar lymphadenopathy. A skin biopsy showed granulomatous nodular dermatitis compatible with sarcoidosis. He was treated with steroid pulse therapy and his neurological and ocular symptoms immediately improved. Only seven similar cases of intracranical sarcoidosis have been reported, but none had been treated with steroid pulse therapy. We recommend that steroid pulse therapy be considered to treat patients with sarcoidosis with signs of lesions in the central nervous system.
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spelling pubmed-32953792012-03-19 Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy Yoshida-Hata, Natsuyo Yashiro, Shigeko Arai, Noritoshi Takeuchi, Sousuke Case Rep Med Case Report A 36-year-old man visited our hospital because of blurred vision and redness of the conjunctiva. Slit-lamp examination showed panuveitis. Two days later, he suddenly experienced dizziness, speech disturbance, paralysis of his right extremities, and gait disturbances. Neurological examinations suggested that his symptoms were caused by a left lateral medullary lesion. He also had erythema mainly on his trunk. Magnetic resonance imaging (MRI) of his brain demonstrated a small infarct on the left side of the medulla oblongata. Clinical presentation and MRI findings were consistent with the diagnosis of a Wallenberg's syndrome. He also had bilateral hilar lymphadenopathy. A skin biopsy showed granulomatous nodular dermatitis compatible with sarcoidosis. He was treated with steroid pulse therapy and his neurological and ocular symptoms immediately improved. Only seven similar cases of intracranical sarcoidosis have been reported, but none had been treated with steroid pulse therapy. We recommend that steroid pulse therapy be considered to treat patients with sarcoidosis with signs of lesions in the central nervous system. Hindawi Publishing Corporation 2012 2012-02-08 /pmc/articles/PMC3295379/ /pubmed/22431930 http://dx.doi.org/10.1155/2012/356743 Text en Copyright © 2012 Natsuyo Yoshida-Hata et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yoshida-Hata, Natsuyo
Yashiro, Shigeko
Arai, Noritoshi
Takeuchi, Sousuke
Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title_full Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title_fullStr Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title_full_unstemmed Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title_short Brainstem Infarction and Panuveitis due to Sarcoidosis Successfully Treated with Steroid Pulse Therapy
title_sort brainstem infarction and panuveitis due to sarcoidosis successfully treated with steroid pulse therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295379/
https://www.ncbi.nlm.nih.gov/pubmed/22431930
http://dx.doi.org/10.1155/2012/356743
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