1,2-Bis[(3,6,9-trimethyl-3,12-ep­oxy-3,4,5,5a,6,7,8,8a,9,10,12,12a-dodeca­hydro­pyrano[4,3-j][1,2]benzodioxepin-4-yl)­oxy]ethane

The title compound, C(32)H(50)O(10), prepared from a mixture of α- and β-dihydro­artemisinin, has two β-arteether moieties linked via an –OCH(2)CH(2)O– bridge, so that the mol­ecule is symmetric about the bridge. Each asymmetric unit contains a β-arteether moiety and an –OCH(2) group, which is only...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Liwei, Yue, Zhengyu, Lv, Dongying, Gao, Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295452/
https://www.ncbi.nlm.nih.gov/pubmed/22412563
http://dx.doi.org/10.1107/S1600536812005089
Descripción
Sumario:The title compound, C(32)H(50)O(10), prepared from a mixture of α- and β-dihydro­artemisinin, has two β-arteether moieties linked via an –OCH(2)CH(2)O– bridge, so that the mol­ecule is symmetric about the bridge. Each asymmetric unit contains a β-arteether moiety and an –OCH(2) group, which is only one-half of the mol­ecule. The endo-peroxide bridges of the parent compounds have been retained in each half of the diol-bridged dimer. The rings exhibit chair and twist-boat conformations.

Ejemplares similares