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2-(2,4,5-Trimeth­oxy­phen­yl)-2,3-dihydro­quinolin-4(1H)-one

In the title aza-flavanone, C(18)H(19)NO(4), an intra­molecular cyclization product of chalcone, the central heterocyclic ring is in an envelope conformation and the dihedral angle between the benzene rings is 51.03 (10)°. The meth­oxy groups at the ortho and para positions are slightly twisted from...

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Detalles Bibliográficos
Autores principales: Chantrapromma, Suchada, Ruanwas, Pumsak, Boonnak, Nawong, Chantrapromma, Kan, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295454/
https://www.ncbi.nlm.nih.gov/pubmed/22412565
http://dx.doi.org/10.1107/S1600536812002917
Descripción
Sumario:In the title aza-flavanone, C(18)H(19)NO(4), an intra­molecular cyclization product of chalcone, the central heterocyclic ring is in an envelope conformation and the dihedral angle between the benzene rings is 51.03 (10)°. The meth­oxy groups at the ortho and para positions are slightly twisted from the benzene ring to which they are bound [C—O—C—C = 21.9 (3) and −171.93 (18)°, respectively], whereas the meth­oxy group at the meta position is almost coplanar [C—O—C—C = 3.5 (3)°]. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds and weak C—H⋯O inter­actions into chains along the [001] direction. Weak C—H⋯π inter­actions also occur.