Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State

The intracellular pathogen Legionella pneumophila hijacks the endoplasmic reticulum (ER)-derived vesicles to create an organelle designated Legionella-containing vacuole (LCV) required for bacterial replication. Maturation of the LCV involved acquisition of Rab1, which is mediated by the bacterial e...

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Detalles Bibliográficos
Autores principales: Cheng, Wei, Yin, Kun, Lu, Defen, Li, Bingqing, Zhu, Deyu, Chen, Yuzhen, Zhang, Hao, Xu, Sujuan, Chai, Jijie, Gu, Lichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295573/
https://www.ncbi.nlm.nih.gov/pubmed/22416225
http://dx.doi.org/10.1371/journal.ppat.1002528

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