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A Human Challenge Model for Mycobacterium tuberculosis Using Mycobacterium bovis Bacille Calmette-Guérin

(See the editorial commentary by Dockrell, on pages 1029–31.) Background. There is currently no safe human challenge model of Mycobacterium tuberculosis infection to enable proof-of-concept efficacy evaluation of candidate vaccines against tuberculosis. In vivo antimycobacterial immunity could be as...

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Detalles Bibliográficos
Autores principales: Minassian, Angela M., Satti, Iman, Poulton, Ian D., Meyer, Joel, Hill, Adrian V. S., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295601/
https://www.ncbi.nlm.nih.gov/pubmed/22396610
http://dx.doi.org/10.1093/infdis/jis012