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Efficient Blockade of Akt signaling is a determinant factor to overcome resistance to Matuzumab
BACKGROUND: Clinical studies have shown antineoplastic effectiveness of monoclonal antibodies (MAbs) against EGFR for different indications. Several MAbs directed to EGFR were developed recently, such as matuzumab, but there is still lack of information on preclinical data on its combination with ch...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295690/ https://www.ncbi.nlm.nih.gov/pubmed/22185378 http://dx.doi.org/10.1186/1476-4598-10-151 |