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Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events

BACKGROUND: Leukemia is a heterogeneous disease commonly associated with recurrent chromosomal translocations that involve tyrosine kinases including BCR-ABL, TEL-PDGFRB and TEL-JAK2. Most studies on the activated tyrosine kinases have focused on proximal signaling events, but little is known about...

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Detalles Bibliográficos
Autores principales:	Kim, Hani, Gillis, Lisa C, Jarvis, Jordan D, Yang, Stuart, Huang, Kai, Der, Sandy, Barber, Dwayne L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295743/ https://www.ncbi.nlm.nih.gov/pubmed/22204395 http://dx.doi.org/10.1186/1471-2407-11-528

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