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Gene Expression of the Tumour Suppressor LKB1 Is Mediated by Sp1, NF-Y and FOXO Transcription Factors

The serine/threonine kinase LKB1 is a tumour suppressor that regulates multiple biological pathways, including cell cycle control, cell polarity and energy metabolism by direct phosphorylation of 14 different AMP-activated protein kinase (AMPK) family members. Although many downstream targets have b...

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Detalles Bibliográficos
Autores principales: Lützner, Nicolas, De-Castro Arce, Johanna, Rösl, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295762/
https://www.ncbi.nlm.nih.gov/pubmed/22412893
http://dx.doi.org/10.1371/journal.pone.0032590

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