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Renal Failure Affects the Enzymatic Activities of the Three First Steps in Hepatic Heme Biosynthesis in the Acute Intermittent Porphyria Mouse
Chronic kidney disease is a long-term complication in acute intermittent porphyria (AIP). The pathophysiological significance of hepatic overproduction of the porphyrin precursors aminolevulinate acid (ALA) and porphobilinogen (PBG) in chronic kidney disease is unclear. We have investigated the effe...
Autores principales: | Unzu, Carmen, Sampedro, Ana, Sardh, Eliane, Mauleón, Itsaso, Enríquez de Salamanca, Rafael, Prieto, Jesús, Salido, Eduardo, Harper, Pauline, Fontanellas, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295788/ https://www.ncbi.nlm.nih.gov/pubmed/22412963 http://dx.doi.org/10.1371/journal.pone.0032978 |
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