The Influence of cis-Regulatory Elements on DNA Methylation Fidelity

It is now established that, as compared to normal cells, the cancer cell genome has an overall inverse distribution of DNA methylation (“methylome”), i.e., predominant hypomethylation and localized hypermethylation, within “CpG islands” (CGIs). Moreover, although cancer cells have reduced methylatio...

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Detalles Bibliográficos
Autores principales: Teng, Mingxiang, Balch, Curt, Liu, Yunlong, Li, Meng, Huang, Tim H. M., Wang, Yadong, Nephew, Kenneth P., Li, Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295790/
https://www.ncbi.nlm.nih.gov/pubmed/22412954
http://dx.doi.org/10.1371/journal.pone.0032928

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