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Optimized labeling of NOTA-conjugated octreotide with F-18

We recently reported a facile method based on the chelation of [(18)F]aluminum fluoride (Al(18)F) by NOTA (1,4,7-triazacyclononane-1,4,7-triacetic acid). Here, we present a further optimization of the (18)F labeling of NOTA-octreotide (IMP466). Octreotide was conjugated with the NOTA chelate and was...

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Detalles Bibliográficos
Autores principales: Laverman, Peter, D’Souza, Christopher A., Eek, Annemarie, McBride, William J., Sharkey, Robert M., Oyen, Wim J. G., Goldenberg, David M., Boerman, Otto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296034/
https://www.ncbi.nlm.nih.gov/pubmed/22009690
http://dx.doi.org/10.1007/s13277-011-0250-x