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Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment

Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relatio...

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Autores principales: Morgan, Douglas R., Benshoff, Matthew, Cáceres, Mercedes, Becker-Dreps, Sylvia, Cortes, Loreto, Martin, Christopher F., Schmulson, Max, Peña, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296149/
https://www.ncbi.nlm.nih.gov/pubmed/22474433
http://dx.doi.org/10.1155/2012/343812
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author Morgan, Douglas R.
Benshoff, Matthew
Cáceres, Mercedes
Becker-Dreps, Sylvia
Cortes, Loreto
Martin, Christopher F.
Schmulson, Max
Peña, Rodolfo
author_facet Morgan, Douglas R.
Benshoff, Matthew
Cáceres, Mercedes
Becker-Dreps, Sylvia
Cortes, Loreto
Martin, Christopher F.
Schmulson, Max
Peña, Rodolfo
author_sort Morgan, Douglas R.
collection PubMed
description Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the “nonsterile” developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire. Stool samples from cases and randomly selected controls were examined for ova and parasites. Logistic regression models explored the relationship between IBS and parasite infection. The overall IBS prevalence among participants was 13.2% (9.3% males, 15.9% females). There was no difference in parasite carriage between IBS cases and controls, 16.6% versus 15.4% (P = 0.78), nor among IBS subtypes. The pathophysiology of post-infectious IBS may be altered in the developing world as compared to industrialized nations and warrants investigation.
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spelling pubmed-32961492012-04-03 Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment Morgan, Douglas R. Benshoff, Matthew Cáceres, Mercedes Becker-Dreps, Sylvia Cortes, Loreto Martin, Christopher F. Schmulson, Max Peña, Rodolfo Gastroenterol Res Pract Research Article Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the “nonsterile” developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire. Stool samples from cases and randomly selected controls were examined for ova and parasites. Logistic regression models explored the relationship between IBS and parasite infection. The overall IBS prevalence among participants was 13.2% (9.3% males, 15.9% females). There was no difference in parasite carriage between IBS cases and controls, 16.6% versus 15.4% (P = 0.78), nor among IBS subtypes. The pathophysiology of post-infectious IBS may be altered in the developing world as compared to industrialized nations and warrants investigation. Hindawi Publishing Corporation 2012 2012-02-19 /pmc/articles/PMC3296149/ /pubmed/22474433 http://dx.doi.org/10.1155/2012/343812 Text en Copyright © 2012 Douglas R. Morgan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Morgan, Douglas R.
Benshoff, Matthew
Cáceres, Mercedes
Becker-Dreps, Sylvia
Cortes, Loreto
Martin, Christopher F.
Schmulson, Max
Peña, Rodolfo
Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title_full Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title_fullStr Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title_full_unstemmed Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title_short Irritable Bowel Syndrome and Gastrointestinal Parasite Infection in a Developing Nation Environment
title_sort irritable bowel syndrome and gastrointestinal parasite infection in a developing nation environment
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296149/
https://www.ncbi.nlm.nih.gov/pubmed/22474433
http://dx.doi.org/10.1155/2012/343812
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