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Silencing of Amyloid Precursor Protein Expression Using a New Engineered Delta Ribozyme

Alzheimer's disease (AD) etiological studies suggest that an elevation in amyloid-β peptides (Aβ) level contributes to aggregations of the peptide and subsequent development of the disease. The major constituent of these amyloid peptides is the 1 to 40–42 residue peptide (Aβ (40−42)) derived fr...

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Detalles Bibliográficos
Autores principales:	Ben Aissa, Manel, April, Marie-Claude, Bergeron, Lucien-Junior, Perreault, Jean-Pierre, Levesque, Georges
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296272/ https://www.ncbi.nlm.nih.gov/pubmed/22482079 http://dx.doi.org/10.1155/2012/947147

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