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IQGAP Family Members in Yeast, Dictyostelium, and Mammalian Cells

IQGAPs are a family of scaffolding proteins with multiple domains, named for the IQ motifs and GTPase activating protein (GAP) related domains. Despite their GAP homology, IQGAP proteins act as effectors for GTP-bound GTPases of the Ras superfamily and do not stimulate GTP hydrolysis. IQGAPs are fou...

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Detalles Bibliográficos
Autor principal: Shannon, Katie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296274/
https://www.ncbi.nlm.nih.gov/pubmed/22505937
http://dx.doi.org/10.1155/2012/894817