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Clinical evaluation of Kushmanda Ghrita in the management of depressive illness

Depressive illness has been considered as a problematic mental illness since antiquity. The treatment modalities of depressive illness are of many kinds. Use of Medhya Rasayana drugs is a unique method of treatment described in Ayurveda for depressive illness. Kushmanda (Benincasa hispida) is one of...

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Autores principales: Chandre, Rajni, Upadhyay, B. N., Murthy, K. H. H. V. S. S. Narasimha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296346/
https://www.ncbi.nlm.nih.gov/pubmed/22408308
http://dx.doi.org/10.4103/0974-8520.92592
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author Chandre, Rajni
Upadhyay, B. N.
Murthy, K. H. H. V. S. S. Narasimha
author_facet Chandre, Rajni
Upadhyay, B. N.
Murthy, K. H. H. V. S. S. Narasimha
author_sort Chandre, Rajni
collection PubMed
description Depressive illness has been considered as a problematic mental illness since antiquity. The treatment modalities of depressive illness are of many kinds. Use of Medhya Rasayana drugs is a unique method of treatment described in Ayurveda for depressive illness. Kushmanda (Benincasa hispida) is one of the Medhya Rasayana as described by Bhava Mishra. Ghrita is also considered as Medhya Rasayana by almost all Acharyas. Keeping this background Kushmanda Ghrita has been selected as a trial drug to treat the patients of depressive illness. The study was carried out in 35 clinically diagnosed cases of depressive illness by using DSM-IV diagnostic criteria of depressive illness. All patients were given 20 ml of Kushmanda Ghrita in two divided doses morning and evening with 40 ml of lukewarm water for a period of one month. It has shown statistically significant results with psychometric parameters–Hamilton depression rating scale (t = 24.36, P < 0.001), Hamilton anxiety rating scale (t = 26.20, P < .001), immediate memory span direct (t = 4.35, P < 0.001), and indirect test (t = 3.43, P < 01) along with clinical symptoms.
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spelling pubmed-32963462012-03-09 Clinical evaluation of Kushmanda Ghrita in the management of depressive illness Chandre, Rajni Upadhyay, B. N. Murthy, K. H. H. V. S. S. Narasimha Ayu Clinical Research Depressive illness has been considered as a problematic mental illness since antiquity. The treatment modalities of depressive illness are of many kinds. Use of Medhya Rasayana drugs is a unique method of treatment described in Ayurveda for depressive illness. Kushmanda (Benincasa hispida) is one of the Medhya Rasayana as described by Bhava Mishra. Ghrita is also considered as Medhya Rasayana by almost all Acharyas. Keeping this background Kushmanda Ghrita has been selected as a trial drug to treat the patients of depressive illness. The study was carried out in 35 clinically diagnosed cases of depressive illness by using DSM-IV diagnostic criteria of depressive illness. All patients were given 20 ml of Kushmanda Ghrita in two divided doses morning and evening with 40 ml of lukewarm water for a period of one month. It has shown statistically significant results with psychometric parameters–Hamilton depression rating scale (t = 24.36, P < 0.001), Hamilton anxiety rating scale (t = 26.20, P < .001), immediate memory span direct (t = 4.35, P < 0.001), and indirect test (t = 3.43, P < 01) along with clinical symptoms. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3296346/ /pubmed/22408308 http://dx.doi.org/10.4103/0974-8520.92592 Text en Copyright: © AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Chandre, Rajni
Upadhyay, B. N.
Murthy, K. H. H. V. S. S. Narasimha
Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title_full Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title_fullStr Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title_full_unstemmed Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title_short Clinical evaluation of Kushmanda Ghrita in the management of depressive illness
title_sort clinical evaluation of kushmanda ghrita in the management of depressive illness
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296346/
https://www.ncbi.nlm.nih.gov/pubmed/22408308
http://dx.doi.org/10.4103/0974-8520.92592
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