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Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting
Viral infection depends on a complex interplay between host and viral factors. Here, we link host susceptibility to viral infection to a network encompassing sulfur metabolism, tRNA modification, competitive binding, and programmed ribosomal frameshifting (PRF). We first demonstrate that the iron-su...
Autores principales: | Maynard, Nathaniel D, Macklin, Derek N, Kirkegaard, Karla, Covert, Markus W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296357/ https://www.ncbi.nlm.nih.gov/pubmed/22294093 http://dx.doi.org/10.1038/msb.2011.101 |
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