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Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease
BACKGROUND: The activation of mononuclear phagocytes (MPs), including monocytes, macrophages and dendritic cells, contributes to central nervous system inflammation in various neurological diseases. In HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), MPs are reservoirs of HTLV-I,...
Autores principales: | Enose-Akahata, Yoshimi, Matsuura, Eiji, Tanaka, Yuetsu, Oh, Unsong, Jacobson, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296610/ https://www.ncbi.nlm.nih.gov/pubmed/22335964 http://dx.doi.org/10.1186/1742-4690-9-16 |
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