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Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296629/ https://www.ncbi.nlm.nih.gov/pubmed/22348469 http://dx.doi.org/10.1186/1477-7819-10-45 |
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author | Takechi, Rumi Yanagawa, Takashi Shinozaki, Tetsuya Fukuda, Toshio Takagishi, Kenji |
author_facet | Takechi, Rumi Yanagawa, Takashi Shinozaki, Tetsuya Fukuda, Toshio Takagishi, Kenji |
author_sort | Takechi, Rumi |
collection | PubMed |
description | The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant therapy and a bone graft gave immediate pain relief. Histological examination of the surgical specimen showed typical features of solid ABC, and cycloxygenase-2 (COX-2) expression was confirmed in giant cells with a background of spindle cells by immunohistochemistry. Magnetic resonance imaging showed that soft tissue edema surrounding the lesion was improved two months after surgery and there was no indication of recurrence two years after surgery. If COX-2 secreted from the tumor induces soft tissue edema, simple curettage of the bone lesion seems to be a reasonable treatment for solid ABC and is able to minimize invasive treatment of the patients. |
format | Online Article Text |
id | pubmed-3296629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32966292012-03-08 Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report Takechi, Rumi Yanagawa, Takashi Shinozaki, Tetsuya Fukuda, Toshio Takagishi, Kenji World J Surg Oncol Case Report The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant therapy and a bone graft gave immediate pain relief. Histological examination of the surgical specimen showed typical features of solid ABC, and cycloxygenase-2 (COX-2) expression was confirmed in giant cells with a background of spindle cells by immunohistochemistry. Magnetic resonance imaging showed that soft tissue edema surrounding the lesion was improved two months after surgery and there was no indication of recurrence two years after surgery. If COX-2 secreted from the tumor induces soft tissue edema, simple curettage of the bone lesion seems to be a reasonable treatment for solid ABC and is able to minimize invasive treatment of the patients. BioMed Central 2012-02-20 /pmc/articles/PMC3296629/ /pubmed/22348469 http://dx.doi.org/10.1186/1477-7819-10-45 Text en Copyright ©2012 Takechi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Takechi, Rumi Yanagawa, Takashi Shinozaki, Tetsuya Fukuda, Toshio Takagishi, Kenji Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title | Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title_full | Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title_fullStr | Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title_full_unstemmed | Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title_short | Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
title_sort | solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296629/ https://www.ncbi.nlm.nih.gov/pubmed/22348469 http://dx.doi.org/10.1186/1477-7819-10-45 |
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