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Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report

The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant th...

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Autores principales: Takechi, Rumi, Yanagawa, Takashi, Shinozaki, Tetsuya, Fukuda, Toshio, Takagishi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296629/
https://www.ncbi.nlm.nih.gov/pubmed/22348469
http://dx.doi.org/10.1186/1477-7819-10-45
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author Takechi, Rumi
Yanagawa, Takashi
Shinozaki, Tetsuya
Fukuda, Toshio
Takagishi, Kenji
author_facet Takechi, Rumi
Yanagawa, Takashi
Shinozaki, Tetsuya
Fukuda, Toshio
Takagishi, Kenji
author_sort Takechi, Rumi
collection PubMed
description The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant therapy and a bone graft gave immediate pain relief. Histological examination of the surgical specimen showed typical features of solid ABC, and cycloxygenase-2 (COX-2) expression was confirmed in giant cells with a background of spindle cells by immunohistochemistry. Magnetic resonance imaging showed that soft tissue edema surrounding the lesion was improved two months after surgery and there was no indication of recurrence two years after surgery. If COX-2 secreted from the tumor induces soft tissue edema, simple curettage of the bone lesion seems to be a reasonable treatment for solid ABC and is able to minimize invasive treatment of the patients.
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spelling pubmed-32966292012-03-08 Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report Takechi, Rumi Yanagawa, Takashi Shinozaki, Tetsuya Fukuda, Toshio Takagishi, Kenji World J Surg Oncol Case Report The solid variant of aneurysmal bone cyst (solid ABC) is rarely encountered in long bones and appropriate treatment for this disease remains unclear. We experienced a 13-year-old boy suffering from pain in his left knee caused by solid ABC. Simple curettage of the bone lesion without any adjuvant therapy and a bone graft gave immediate pain relief. Histological examination of the surgical specimen showed typical features of solid ABC, and cycloxygenase-2 (COX-2) expression was confirmed in giant cells with a background of spindle cells by immunohistochemistry. Magnetic resonance imaging showed that soft tissue edema surrounding the lesion was improved two months after surgery and there was no indication of recurrence two years after surgery. If COX-2 secreted from the tumor induces soft tissue edema, simple curettage of the bone lesion seems to be a reasonable treatment for solid ABC and is able to minimize invasive treatment of the patients. BioMed Central 2012-02-20 /pmc/articles/PMC3296629/ /pubmed/22348469 http://dx.doi.org/10.1186/1477-7819-10-45 Text en Copyright ©2012 Takechi et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Takechi, Rumi
Yanagawa, Takashi
Shinozaki, Tetsuya
Fukuda, Toshio
Takagishi, Kenji
Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title_full Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title_fullStr Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title_full_unstemmed Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title_short Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
title_sort solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296629/
https://www.ncbi.nlm.nih.gov/pubmed/22348469
http://dx.doi.org/10.1186/1477-7819-10-45
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