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A Metalloproteinase Secreted by Streptococcus pneumoniae Removes Membrane Mucin MUC16 from the Epithelial Glycocalyx Barrier
The majority of bacterial infections occur across wet-surfaced mucosal epithelia, including those that cover the eye, respiratory tract, gastrointestinal tract and genitourinary tract. The apical surface of all these mucosal epithelia is covered by a heavily glycosylated glycocalyx, a major componen...
Autores principales: | Govindarajan, Bharathi, Menon, Balaraj B., Spurr-Michaud, Sandra, Rastogi, Komal, Gilmore, Michael S., Argüeso, Pablo, Gipson, Ilene K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296694/ https://www.ncbi.nlm.nih.gov/pubmed/22412870 http://dx.doi.org/10.1371/journal.pone.0032418 |
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