Prolyl Isomerase Pin1 Regulates Mouse Embryonic Fibroblast Differentiation into Adipose Cells

BACKGROUND: A peptidyl prolyl cis/trans isomerase, Pin1, regulates insulin signal transduction. Pin1 reduces responses to insulin stimulation by binding CRTC2 (CREB-regulated transcriptional co-activator 2) and PPARγ (peroxisome prolifereator- activated receptor γ), but conversely enhances insulin s...

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Detalles Bibliográficos
Autores principales: Uchida, Takafumi, Furumai, Kengo, Fukuda, Tomokazu, Akiyama, Hirotada, Takezawa, Mika, Asano, Tomoichiro, Fujimori, Fumihiro, Uchida, Chiyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296696/
https://www.ncbi.nlm.nih.gov/pubmed/22412843
http://dx.doi.org/10.1371/journal.pone.0031823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296696/
https://www.ncbi.nlm.nih.gov/pubmed/22412843
http://dx.doi.org/10.1371/journal.pone.0031823

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