Regulation of GIP and GLP1 Receptor Cell Surface Expression by N-Glycosylation and Receptor Heteromerization

In response to a meal, Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-like Peptide-1 (GLP-1) are released from gut endocrine cells into the circulation and interact with their cognate G-protein coupled receptors (GPCRs). Receptor activation results in tissue-selective pleiotropic re...

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Detalles Bibliográficos
Autores principales: Whitaker, Gina M., Lynn, Francis C., McIntosh, Christopher H. S., Accili, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296735/
https://www.ncbi.nlm.nih.gov/pubmed/22412906
http://dx.doi.org/10.1371/journal.pone.0032675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296735/
https://www.ncbi.nlm.nih.gov/pubmed/22412906
http://dx.doi.org/10.1371/journal.pone.0032675

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