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Amplified Genes May Be Overexpressed, Unchanged, or Downregulated in Cervical Cancer Cell Lines

Several copy number-altered regions (CNAs) have been identified in the genome of cervical cancer, notably, amplifications of 3q and 5p. However, the contribution of copy-number alterations to cervical carcinogenesis is unresolved because genome-wide there exists a lack of correlation between copy-nu...

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Detalles Bibliográficos
Autores principales: Vazquez-Mena, Oscar, Medina-Martinez, Ingrid, Juárez-Torres, Eligia, Barrón, Valeria, Espinosa, Ana, Villegas-Sepulveda, Nicolás, Gómez-Laguna, Laura, Nieto-Martínez, Karem, Orozco, Lorena, Roman-Basaure, Edgar, Muñoz Cortez, Sergio, Borges Ibañez, Manuel, Venegas-Vega, Carlos, Guardado-Estrada, Mariano, Rangel-López, Angélica, Kofman, Susana, Berumen, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296745/
https://www.ncbi.nlm.nih.gov/pubmed/22412903
http://dx.doi.org/10.1371/journal.pone.0032667

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